000 03775nam a22005055i 4500
001 978-1-4939-0679-6
003 DE-He213
005 20160302172501.0
007 cr nn 008mamaa
008 140523s2014 xxu| s |||| 0|eng d
020 _a9781493906796
_9978-1-4939-0679-6
024 7 _a10.1007/978-1-4939-0679-6
_2doi
050 4 _aQH573-671
072 7 _aPSF
_2bicssc
072 7 _aSCI017000
_2bisacsh
072 7 _aSCI049000
_2bisacsh
082 0 4 _a571.9453
_223
245 1 0 _aStudies on Pediatric Disorders
_h[electronic resource] /
_cedited by Hirokazu Tsukahara, Kazunari Kaneko.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2014.
300 _aXII, 494 p. 115 illus., 53 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aOxidative Stress in Applied Basic Research and Clinical Practice,
_x2197-7224
505 0 _aOxygen in health and disease -- Reactive oxygen species and nitric oxide in vascular function -- Nitrite pathway: Another important nitric oxide production system -- Nitric oxide and beyond: New insights and therapies for endothelial targeting -- Multifunctional roles of nitric oxide in neurons -- Oxidative stress biomarkers: Future perspectives -- Urinary clinical biomarkers in critical care -- Rapid diagnostic tests for oxidative stress status -- Analytical procedures for nitrative/nitrosative stress -- Animal models of enhanced oxidative stress -- Antioxidant supplementation and therapies -- Edaravone therapy -- Melatonin therapy -- Thioredoxin therapy -- Allergic and immunological disorders -- Cardiac disorders -- Environmental pollution and health consequences -- Gastrointestinal disorders -- Genetic disorders -- Growth, puberty and nutritional disturbances -- Hematologic disorders -- Infectious and inflammatory disorders -- Metabolic disorders -- Neurological disorders -- Renal disorders -- Respiratory disorders -- Trauma -- Vascular disorders.
520 _aThis volume examines the role of oxidative stress in the pathology of numerous pediatric disorders. It covers a wide range of topics including the chemistry and biology of reactive oxygen species and nitric oxide, molecular biology of the enzymes generating these species, clinically useful biomarkers for evaluating oxidative stress status in humans, and the pathophysiology, clinical course and management of a variety of pediatric disorders, among others. The book also describes current diagnostic tools, laboratory methods and technology for treatment and prevention of pediatric disorders.� It explores emerging technology and medical applications including discussions of biomarkers and antioxidants as therapeutic agents. Written by an international team of experts in both pediatrics and� free radical and antioxidant research, Studies on Pediatric Disorders is an invaluable addition to the Oxidative Stress in Applied Basic Research and Clinical Practice series.
650 0 _aLife sciences.
650 0 _aPediatrics.
650 0 _aCell biology.
650 0 _aOxidative stress.
650 1 4 _aLife Sciences.
650 2 4 _aOxidative Stress.
650 2 4 _aPediatrics.
650 2 4 _aCell Biology.
700 1 _aTsukahara, Hirokazu.
_eeditor.
700 1 _aKaneko, Kazunari.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781493906789
830 0 _aOxidative Stress in Applied Basic Research and Clinical Practice,
_x2197-7224
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4939-0679-6
912 _aZDB-2-SBL
999 _c205843
_d205843