MARC details
| 000 -LEADER |
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| fixed length control field |
05132nam a22005175i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-3-540-92165-3 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20160302164740.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
100301s2009 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783540921653 |
| -- |
978-3-540-92165-3 |
| 024 7# - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1007/978-3-540-92165-3 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
QR355-502 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MMFM |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
MED052000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
616.9101 |
| Edition number |
23 |
| 245 10 - TITLE STATEMENT |
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| Title |
Vaccines for Pandemic Influenza |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc. |
edited by Richard W. Compans, Walter A. Orenstein. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Berlin, Heidelberg : |
| Name of producer, publisher, distributor, manufacturer |
Springer Berlin Heidelberg, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2009. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XVIII, 512 p. 51 illus., 30 illus. in color. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
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| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
|---|
| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 490 1# - SERIES STATEMENT |
|---|
| Series statement |
Current Topics in Microbiology and Immunology, |
| International Standard Serial Number |
0070-217X ; |
| Volume/sequential designation |
333 |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Pandemic Influenza Overview -- Pandemic Influenza as a Current Threat -- Antigenic Cross-Reactivity Among H5N1 Viruses -- Current Approaches for Human and Avian Vaccine Production -- Seasonal Influenza Vaccines -- Generation and Characterization of Candidate Vaccine Viruses for Prepandemic Influenza Vaccines -- Live Attenuated Vaccines for Pandemic Influenza -- Influenza Vaccines for Avian Species -- Development and Application of Avian Influenza Vaccines in China -- Novel Vaccine Approaches -- Designing Vaccines for Pandemic Influenza -- Attenuated Influenza Virus Vaccines with Modified NS1 Proteins -- DNA Vaccines Against Influenza Viruses -- Recombinant Proteins Produced in Insect Cells -- Influenza Neuraminidase as a Vaccine Antigen -- Recombinant Vectors as Influenza Vaccines -- Influenza Virus-Like Particles as Pandemic Vaccines -- Pandemic Influenza Vaccines -- Adjuvants for Pandemic Influenza Vaccines -- Novel Approaches for Vaccine Delivery -- Transcutaneous Immunization with Influenza Vaccines -- Microneedle-Based Vaccines -- Vaccine Evaluation, Production and Distribution -- Animal Models for Evaluation of Influenza Vaccines -- Immunosenescence and Influenza Vaccine Efficacy -- Vaccines for Pandemic Influenza: Summary of Recent Clinical Trials -- Considerations for Licensure of Influenza Vaccines with Pandemic and Prepandemic Indications -- Strategies for Broad Global Access to Pandemic Influenza Vaccines -- Prioritization of Pandemic Influenza Vaccine: Rationale and Strategy for Decision Making. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Recent years have seen unprecedented outbreaks of avian influenza A viruses. In particular, highly pathogenic H5N1 viruses have not only resulted in widespread outbreaks in domestic poultry, but have been transmitted to humans resulting in numerous fatalities. The rapid expansion in their geographic distribution and the possibility that these viruses could acquire the ability to spread from person to person raise the risk that such a virus could cause a global pandemic with high morbidity and mortality. An effective influenza vaccine represents the best approach to prevent and control such an emerging pandemic. However, current influenza vaccines are directed at existing seasonal influenza viruses, which have limited antigenic relationships to the highly pathogenic H5N1 strains. Concerns about pandemic preparedness have greatly stimulated research activities to develop effective vaccines for pandemic influenza viruses, and to overcome the limitations inherent in current approaches to vaccine production and distribution. These limitations include the use of embryonated chicken eggs as the substrate for vaccine production; which is time-consuming and could involve potential biohazards in growth of new virus strains. Other limitations include the requirement that the current inactivated influenza vaccines be administered using needles and syringes, requiring trained personnel, which could be a bottleneck when attempting to vaccinate large populations in mass campaigns. In addition, the current inactivated vaccines which are delivered by injection elicit limited protective immunity in the upper respiratory tract where the infection process is initiated. Most of these limitations of the current vaccines are being addressed by research on novel approaches to vaccine development and delivery that are described in many of the chapters in this volume. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Immunology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Pharmacology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Virology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Public health. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Virology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Pharmacology/Toxicology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Public Health. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Immunology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Compans, Richard W. |
| Relator term |
editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Orenstein, Walter A. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9783540921646 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
|---|
| Uniform title |
Current Topics in Microbiology and Immunology, |
| International Standard Serial Number |
0070-217X ; |
| Volume number/sequential designation |
333 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
<a href="http://dx.doi.org/10.1007/978-3-540-92165-3">http://dx.doi.org/10.1007/978-3-540-92165-3</a> |
| 912 ## - |
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| -- |
ZDB-2-SBL |
